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IUI vs. IVF: When to Consider Each in Fertility Treatment

Sep 08, 2025
Fertility treatments can feel overwhelming. IUI and IVF are two common options that help with conception in different ways. Understanding when to use each can help you take the next step with confidence.

What is IUI?

Intrauterine Insemination (IUI) is often one of the first fertility treatments recommended. During IUI, prepared sperm is placed directly into the uterus around the time of ovulation. This increases the chances of sperm meeting the egg naturally.

IUI is generally considered when:

  • There are mild male factor issues, such as low sperm count or motility.
  • The woman has regular ovulation and open fallopian tubes.
  • There are cases of unexplained infertility.
  • Donor sperm is being used.

Because it is less invasive and more affordable than IVF, many couples or individuals start with IUI as a first step. However, its success rates are lower compared to IVF, particularly for women over 35 or those with more complex fertility challenges.

What is IVF?

In Vitro Fertilization (IVF) is a more advanced treatment. Eggs are retrieved from the ovaries and fertilized with sperm in a lab. Embryos are then grown and transferred into the uterus.

IVF may be recommended when:

  • IUI attempts have been unsuccessful.
  • A woman has blocked fallopian tubes or severe endometriosis.
  • There are more significant male factor infertility issues.
  • The patient is older or has diminished ovarian reserve.
  • Genetic testing (PGT) of embryos is desired.

IVF also provides more control and options—such as freezing embryos for future use or using donor eggs or sperm—making it a powerful choice for many families.

Choosing the Right Path for You

Deciding between IUI and IVF depends on several factors, including age, fertility diagnosis, medical history, and personal preferences. At Gen 5 Fertility, our team will walk you through every option, ensuring that your treatment plan is tailored to your unique needs and goals.

Take the Next Step

If you’re wondering whether IUI or IVF is the right choice for your family-building journey, the experts at Gen 5 Fertility are here to guide you.

Call us at 858-568-6210 or visit Gen5Fertility.com to schedule a consultation and take your first step toward turning the dream of family into reality.